Summary of Oklahoma University Study

Frankincense oil derived from Boswellic Acids induces tumor cell specific cytotoxicity

(http://www.biomedcentral.com/1472-6882/9/6) (complete study)

BMC Complementary and Alternative Medicine 2009

Frankincense has been studied for its anti-tumor activity and signaling pathways in cancer cells.  The Health Sciences departments at the University of Oklahoma found that one of the main components of frankincense oil is boswellic acid, a component known to have anti-neoplastic (anti-tumor) properties. 

Although initial testing was performed using one specific species of Boswellia, all species of Frankincense were shown (using Gas-Chomatography) to have the same unique boswellic acid called 11-keto-β-boswellic acid, or KBA.  

According the this research, KBAs, the most potent anti-inflammatory component of the resin, selectively blocks leukotriene biosynthesis (Leukotrienes are fatty molecules of the immune system that contribute to inflammation),and provides protective effects in ulcerative colitis. In addition, boswellic acids have been shown to possess anti-cancer activities through their cytostatic (Inhibiting or suppressing cellular growth and multiplication) and apoptotic (a genetically directed process of cell self-destruction that is marked by the fragmentation of nuclear DNA) effects in multiple human cancer cell lines including meningioma cells, leukemia cells, hepatoma cells, melanoma cells, fibrosarcoma cells, and colon cancer cells.

The study of Frankincense oil was shown to differentiate bladder cancer cells from normal bladder cells and suppress cancer cell viability, and stop the ‘rapidly multiplying process’ of the cells which ultimately might be responsible for Frankincense oil-induced cell death in those cancerous cells.   Test results are consistent with a news report that Frankincense oil specifically targets malignant melanoma but not normal skin cells in horses http://www.purepeace.com/press/press_frankincense.pdf webcite.

 

 


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